Clinical Challenges of Long Acting Reversible Contraception (LARC)
/Read along with CO 672: Clinical Challenges of Long-Acting Reversible Contraceptive Methods
Increased LARC Use
There has been an increase in LARC use over the last few decades
As high as 13.1% in women 20-29 and 11.7% in women 30-39 years of age in 2018
This is compared to 2.4% of all women in 2002
While overall complication of IUDs and implants are low (<1%), the absolute number of these complications will increase as more patients use them.
Complications with IUDs
Pain with IUD insertion
IUD insertion can be painful, especially for nulliparous women
Unfortunately, a 2015 Cochrane Review concluded that lidocaine 2% gel, NSAIDs, and misoprostol for cervical ripening were not effective for reducing pain associated with insertion
A word on misoprostol use
Can cause nausea and abdominal cramping per some trials
Does also require a delay - can be a barrier to access
Paracervical block
Has demonstrated effectiveness in other office transcervical procedures
Studies have shown reduced pain with tenaculum placement after local injection of anesthetic at the tenaculum site
However, other studies have shown no difference in pain with treatment vs. no treatment
Meta-analysis of various analgesic measures did conclude that lidocaine paracervical block reduces pain scores associated with tenaculum placement and IUD insertion
Recommendation:
Routine misoprostol use before IUD insertion in nulliparous women is not recommended, but can be considered with difficult insertions
Pain with IUD insertion needs to be addressed, and one possible way is via a parcervical block as well as injection of lidocaine at the tenaculum site
One last note: patients’ pain should be believed, and discussion for pain relief should be individualized.
Some patients may require nothing other than oral medications, but if appropriate and after discussion, some patients may require anesthesia and an OR procedure
Nonvisualized strings
The most common reason for nonvisualized IUD strings is string retraction into the cervical canal or uterine cavity
First step: use a cytobrush to sweep the canal and see if strings are retrievable
However, nonvisualized strings can also indicate other complications such as pregnancy, expulsion, or uterine perforation
If strings cannot be visualized after cytobrush, then rule out pregnancy
Can also offer emergency contraception if indicated
Next step is to obtain a pelvic ultrasound
If IUD is not visualized with the pelvic ultrasound, then obtain Xray of the abdomen and pelvis - if not visualized, then IUD is likely expelled
If the IUD is visualized, then this may require laparoscopic removal if there is true perforation and migration
Difficult removal of IUD
If IUD removal is requested, and strings cannot be visualized, alligator forceps can be used to remove the IUD
However, before instrumenting, should confirm that IUD is truly in the uterus
IF strings cannot be visualized, follow above procedure
Malposition/nonfundal position of IUD
If an IUD is in the cervix, this is considered a partial expulsion
Recommendation is to remove the IUD and replace it if it is desired
If an IUD is in the lower uterine segment or low-lying, the ideal management is less clear
Shared decision making - if patient is asymptomatic and IUD is above the internal os, it can be retained and will be effective
However, more studies need to be done to see if failure rates of IUDs are higher when the IUD is located in the lower uterine segment
Also, many IUDs that are non fundal shortly after insertion move to a fundal position after 3 months
Expulsion/Uterine Perforation
Expulsion can happen in 2-10% of users and varies by IUD type and when the IUD is placed
Risk factors include age <20, heavy bleeding, dysmenorrhea, placement immediately postpartum, and anatomic distortion of the uterine cavity
Recommendation: if IUD is found to be expelled, rule out pregnancy and then counsel regarding contraceptive choices
Perforation into the peritoneal cavity is rare and occurs <1/1000 insertions
Recommendation: rule out pregnancy and then surgical removal
Laparoscopy is preferred
However, depending on location of IUD, it may be possible that it should be left in place if surgical risks associated with removal and considered too great
Replacement of another IUD under laparoscopic guidance can be done if patient desires
Infection
IUDs should not placed if there is active infection
Infection after IUD insertion is rare, and while the risk of PID developing is increased in the first 20 days after IUD insertion, the risk drops to baseline population risk after
In patients with PID who have an IUD, the IUD can be left in-situ unless there is no clinical improvement
IUD removal can be considered after this
Pregnancy with IUD in place
The risk of pregnancy with IUD in place is 2% after 10 years, similar to tubal sterilization procedures
Ectopic pregnancy must be ruled out - first obtain pelvic ultrasound
If ectopic pregnancy is present, then this needs to be managed medically or surgically. The IUD can be retained if desired
If there is an intrauterine pregnancy
If undesired, then IUD can be removed at time of surgical abortion or before medical abortion
If desired, then IUD can be removed if strings are visible
If strings are not visualized, then ultrasound should be done
If the IUD is in the cervix, then removal can be attempted
If IUD is above the cervix, then IUD should not be removed; instead, discussion should be had with patient about increased risk of obstetric complication in setting of pregnancy with IUD
These include increased risk of SAB, infection, and preterm delivery
If no IUD is seen, then Xray should be done of the abdomen/pelvis after pregnancy
Complications with Implants
Nonpalpable Implant and Deep Insertion
If an implant is not palpable, first thing is to rule out pregnancy
Do not attempt removal unless implant location is determined
Obtain imaging to locate the implant
As there is barium in the implant, X-ray, CT, and fluoroscopy can all be used
Ultrasound and MRI can also be used if needed
If there is a deep insertion that cannot be removed in office:
Consult with family planning specialist or general surgery for removal
If implant is not deeply located within muscle or near neurovascular bundle, then outpatient removal can be attempted with local anesthesia and ultrasound
If the implant is deeply embedded into muscle or nearby neurovascular bundle, then attempt should only be made in the operating room with specialist or surgeon
If imaging is not able to locate the implant, then an etonogestrel serum assay can be done – if itis negative, then there is no implant in the person’s body
Pregnancy with Implants
Risk overall is <1%, but if pregnancy is confirmed, there is a higher risk of ectopic pregnancy
An ectopic pregnancy should be managed medically or surgically per guidelines
If patient desires termination of pregnancy, the implant can be retained
If the pregnancy is desired, then the implant should be removed
Etonogestrel is not teratogenic