Pessaries for the GYN Patient, feat. Dr. Edward Kim


What are pessaries?

  • Pelvic organ prolapse (or POP) and stress urinary incontinence (or SUI) are common problems that impact millions of women in the world.

  • A pessary is a support device placed vaginally that can be used to treat symptoms of POP, SUI, or both.

    • Pessaries are generally cost effective, well-tolerated, safe and can help avoid surgery.

      • For POP, up to 90% of patients report relief of symptoms like pressure and bulge.

      • For SUI, about half of patients report improvement in urinary symptoms.

History of the pessary

  • Historically, the first use of pessary for reduction of pelvic organ prolapse was described by Hippocrates.

    • He put a halved pomegranate soaked in wine into the vagina.

  • In 1860, Dr. Hugh Lenox Hodge, an ob/gyn faculty at the University of Pennsylvania, used newly developed vulcanized rubber to create a pessary shaped more anatomically.

    • Today, most pessaries are made of soft, flexible silicone thus considered non-allergenic.

The Modern Pessary

  • The most commonly used pessaries are ring, Gellhorn and donut. 

    • Ring pessary is a go-to in practice.

      • Subtypes: Ring without support

      • Ring with support (kinda looks like a mini frisbee),
        Ring without support with a knob

      • Ring with support with a knob.

        • The knob sits under the pubic bone and helps with stress urinary incontinence. So a ring with support and a knob will address POP and SUI. Rings can be removed by patients fairly easily.

    • A Gellhorn has a stem and a concave disc (kinda looks like a baby pacifier).

      • The concave disc part sits below the vaginal apex and creates somewhat of a suction.

      • The stem sits posteriorly and prevents the pessary from flipping around.

        • Gellhorns are little more difficult to place. Patients seldom can remove them on their own.

        • For removal, a provider usually needs to grasp the stem with their fingers or a ring forceps, gently wiggle it out to break the suction allowing for removal.

        • Gellhorns are generally used for more severe prolapse.

    • A donut (as the name implies) looks like a mini donut and it achieves its function by occupying the vagina.

      • A donut works better for more severe prolapse, as well, and difficult for patients to remove on their own.

Indication and counseling:

  • Patients with symptomatic POP or SUI who desire to avoid surgery, poor candidate for surgery, desire further childbearing, current pregnancy or within 12 months postpartum.

  • Contraindications include:

    • active pelvic infection,

    • latex allergy (as some inflatable pessary are composed of latex),

    • non adherence to care and follow up

  • Studies report a very wide range of patient acceptance of pessary: from 42 to 100%.

    • Patients who decline tend to be younger, sexually active,  nulliparous, or have severe POP or SUI and desire surgical correction.

    • But it also depends on the counseling. In our practice, we discuss pessary in the range of management options for POP and SUI. We sometimes use it as a bridge between now and surgery for patients who prefer symptom relief now.

Placement:

  • Placement comes with practice and it often involves trial and error.

  • There have been no identified reliable predictors of which size pessary should be tried first.

  • Start with a ring with support pessary (ring with support and a knob if also trying to address SUI).

  • Identifying the starting size (say, 3, 4, 5) comes with practice and pelvic exam. Wet it with warm water first.

    • You could use lubricant but if you use too much it may be too slippery for you to handle and also easier for it to be expelled.

  • Fold it in half like a taco, insert, and allow it to resume its disc shape in situ. Remember, it should NOT be painful. If the patient says it’s painful once it’s placed, then it is often too big.

    • Liken it to a corrective device like glasses or contact lens. When you first start using it, you notice that it’s there. But it should not be painful and with time you often forget it’s there.

  • Then have pt Valsalva.

    • It’s okay that you can see the pessary descend as long as it does not completely get expelled.

  • Then have them ambulate and go to the toilet and Valsalva with a toilet hat to catch the pessary if it does get expelled.

    • If it’s still in situ after that and patient has no discomfort, we send them home with it.

  • Placement of Gellhorn, donuts, and other types of pessaries are little different and may be best reserved for providers who have more experience with them. But I think ring pessaries can be something everyone can have in their toolbox.

Maintenance:

  • Patients who wish to and have the dexterity to maintain the pessaries on their own are instructed to take it out and clean with warm soapy water as often as they want but usually at least once a week.

    • If they are unable to, then typically they come to the clinic every 3-4 months for maintenance.

  • Patients with Gellhorn, donut, or other types of pessaries that patients cannot remove easily on their own also follow up every 3-4 months. At these visits, the pessary is removed, gently cleaned, and a speculum exam is done to assess for any excoriation or abrasion.

  • For postmenopausal patients without contraindication for topical vaginal estrogen, we typically have them use it to prevent significant vaginal excoriation or abrasion since atrophy can worsen these.

Complications:

  • Most common complaints are increase or change in vaginal discharge or odor. Reassurance and ruling out for vaginitis and bacterial vaginosis are reasonable next steps. Reports of vaginal bleeding long after placement warrants exam in the office.

  • Spontaneous expulsion or difficulty with voiding or defecation or pain often means a different size or shape should be tried.

  • Pessaries that have been left in situ and neglected for prolonged period of time should be taken seriously. Embedded pessaries may need removal under general anesthesia.

  • But overall, it is generally very safe.

Applying to Urogynecology / FPMRS, with Dr. Edward Kim

We welcome back Dr. Edward Kim, an FPMRS fellow at the University of Pennsylvania, who’s talking with us today about how to apply for urogynecology fellowship!

Disclosures: We’re from a large academic institution. What we say may not apply to those from smaller programs or those from community programs! Please feel free to reach out to us though for other specifics or connections on advice.

  1. What is Urogynecology or FPMRS?

    1. Female pelvic medicine and reconstructive surgery

    2. We are a subspecialty of either Ob/Gyn or Urology that focuses on medical management, surgical management and research of women’s pelvic floor conditions. Vast majority of our surgeries are elective and outpatient or at the most overnight stays. Compared to other gyn surgical subspecialties like gyn onc or MIGS, there is very little inpatient care needs or consults. Our patient population is predominantly older patients with exceptions at institutions that do gender affirming surgeries, peripartum pelvic floor care, etc. Our research areas range from basic science to NIH-funded research network.

    3. Historically, the name FPMRS was created to replace or supplement the name urogynecology in order to relay that our scope of practice can go beyond urologic and gynecologic conditions. However, more recently, the name FPMRS is being re-discussed as the word female is not inclusive especially given that more of us are seeing gender diverse patients and perform gender affirming surgeries.

    4. Long story short, urogynecology and FPMRS are synonymous for the time being but it may evolve.

    5. In terms of the duration of training: For Ob/Gyns it’s a 3 year fellowship and for Urologists it’s a 2 year fellowship. For Ob/Gyns, these 3 years include 12 months of research, as it is for all ABOG certified subspecialties.

    6. Your training will cover a variety of pelvic floor conditions as defined by American Urogynecologic Society’s (AUGS) scope of practice:

      1. Urinary Incontinence

      2. Pelvic organ prolapse

      3. Voiding dysfunction

      4. Neurogenic bladder

      5. Urethral diverticula

      6. Vesico-vaginal and recto-vaginal fistulae

      7. Congenital anomalies of the pelvic floor

      8. Fecal incontinence

      9. Recurrent UTI

      10. IC/BPS

      11. Managing pelvic floor surgery complications and mesh complications

      12. And at some programs:

a)    Transgender care and gender affirming surgeries

b)    Peripartum pelvic floor care

c)     Pelvic pain

d)    Etc.

 

  1. Years I - II

    1. NOTE: Urogyn is EARLY application and EARLY match just like Urology. Urogyn timeline is thus a few months earlier than other Ob/Gyn subspecialties. Applications OPEN in NOVEMBER/DECEMBER and CLOSE by January of PGY3 year, interview in SPRING of PGY3 year and match by AUGUST of PGY4 year. So solidifying your interest in urogyn earlier in residency is beneficial.

    2. If you are at a residency with big urogyn presence and have fellowship. Typically you will rotate through or be exposed to urogyn as junior residents. If so,

      1. See what your attendings and fellows do. Talk to them about why they went into it. Do you like major and minor urogyn surgeries? How about the predominantly older patient population?

      2. See what kind of scholarly activities are happening in the division. Ask if you can be more involved with research. This will help you get “plugged in” with the division.

      3. Do well on CREOGs but not a huge deal until your third year. Show an upward trend if you can.

    3. If you are not at a residency with big urogyn presence

      1. Identify a local urogyn faculty or urogyn division.

      2. If your residency and host institution allow, do an away rotation. Try to impress them and get a great letter. Ideally, you should have at least one urogyn write a letter of recommendaiton for you.

      3. At the least, do scholarly work like a book chapter or full on research project.

    4. PGY2s should consider either:

      1. AUGS Resident Scholars Program that gives funding to attend AUGS meeting to network and be exposed to the greater urogyn world

      2. ABLE Scholar Travel Award that is similar to the resident scholars program but focused on residents from diverse backgrounds

      3. You can apply as a PGY3, but by the time you attend AUGS, your fellowship application process will already be in full swing. So try to go in PGY2 year to network if you can.

  2. Third Year

    1. Identify people that can write your letter of recommendation.

    2. Continue your research projects and other scholarly activities

    3. If you haven’t already, apply for either resident scholar programs that I mentioned

    4. Applications open in November/December!

      1. So in the summer/early fall time, look at AUGS’ listing of fellowship programs. Look at each program’s information. Make a list of programs you’d be interested in

      2. Sit down with your mentor/fellows and edit or add to the list

a)    Talk about: research heavy? Academic versus private after graduation? Specific niches like gender affirming care, basic science research, dual degree opportunities?

  1. Applications

    1. Overview: Applications open in November/December and close in January typically. Interview invitations will be sent out around February. Interviews are from March to June. With the match in August.

    2. In early fall of PGY3 year, update your CV and get the application material together.

    3. Write your personal statement and have your mentors review it. Help the readers understand why urogyn and what you want to accomplish in your career.

    4. Most programs will not review the application as soon as the application opens in Nov/Dec. Do submit on the earlier side because you don’t know what the process is like at your top choice programs. But don’t rush at the cost of making mistakes in your application.

    5. All programs will send out interview invites on a single designated day typically in February.

      1. Just like in residency, be prompt about responding to interview invites as to not end up on the waitlist.

  2. Interviews

    1. Back in our day for Nick Fei and I, we spent a lot of money on in-person interviews! Virtual interviews are wallet-friendly and schedule-friendly, but they are also exhausting! Allow yourself some breaks and downtime between interviews if you can and try to optimize the number of interviews you do.

    2. You all know this by this point in your career but:

      1. Do your homework on the program! Some programs have good information about their programs on their websites or on their AUGS program listing. Try not to ask questions that is reasonably evident lest you want to be seen as not interested in the program. Ask people you know about the programs. Networking at AUGS will come in handy.

      2. Know the program faculty and what their interests are

      3. Have a list of questions:

a)    Surgical modality breakdown: robotic, vaginal, laparoscopic, etc.

b)    What kinds of non-bread and butter urogyn things do they do? Gender affirming care, peripartum pelvic floor issues, etc.?

c)     What is their research year structure? One full year? Or 12 months broken up throughout?

d)    What kinds of research do their fellows do? Basic science? Clinical?

      1. For logistical questions like calls, transportations, try to save those for the fellows or perhaps the PD

    1. It’s hard to get a sense on virtual interview days but try to see if the division members seem friendly and collegial with one another.

    2. See if everyone in the division makes it to the interview. Programs that are vested in their fellowship will try very hard to pick a time and day that works for everyone, block out their ORs and clinics, etc.

  1. Rank Lists

    1. Make your rank list and seek feedback from your mentors. Think about geography and what you want in a program. 3 years is a long time and you will have a lot more free time in urogyn fellowship compared to residency or even other ob/gyn subspecialties! So being at a place that you can be with family, friends, or things you like doing are also something to consider.

    2. Be sure to reach out to a few programs that you really loved. You voluntarily telling your top choices that they are your top choices is not against the NRMP rules.

      1. Some programs do not write back at all.

      2. To really support your emails of interest; Ask your mentors to reach out on your behalf.

    3. It’s hard to know which programs want thank you emails or not. Try to lean on the side of doing them. Again, some program and interviewers will not write back. That’s okay!

Microscopic Hematuria

Committee Opinion 703 serves for additional reading today!

Defining Microscopic Hematuria

  • 2012 American Urologic Association (AUA) criteria - 3+ RBC/high power field

  • The AUA guidelines also noted that if found, recommendation for evaluation for all patients older than age 35 years

    • This evaluation includes cystoscopy and upper urinary tract imaging with CT, with the primary concern being urothelial malignancy

  • The data supporting this approach was largely based on male patients - so ACOG and AUGS put together this series of recommendations thinking about the female patient 

    • As an example of how this can be so different: the CO points to a large study where 20% of urinalyses performed had microscopic hematuria, and other studies pointing to incidences between 2% and 31% – that would be a lot of studies!

  • These studies do carry risks – radiation and malignancy risk, particularly for young patients.

Differential Diagnosis and Risk Factors

  • ACOG points to specimen collection being potentially more challenging in women:

    • Hematuria might result from true hematuria, but also from

      • Menstruation

      • Urogenital tract atrophy

      • Pelvic organ prolapse

      • Other non-threatening urogenital diagnosis (prostatic hypertrophy in men, urethral stricture, etc). – these are much less common in women as well.

    • The primary concern with microscopic hematuria: urothelial malignancy.

      • Risk factors:

        • Male sex

        • Age over 50

        • Previous or current smoker

        • Gross hematuria

        • HIstory of pelvic radiation

      • Male sex specifically has 3.3x more new cases of bladder cancer than female sex

        • 4th most common cancer in men, while not in the top 10 cancers for women

      • Renal cancer is also 1.7x more likely in men.

When is reasonable to consider screening in women?

  • Studies looking at women have found:

    • Urologic malignancy rate in women under 40 years with any microscopic hematuria was 0.02%, and older than 40 years was 0.4%

    • Urologic malignancy rate is higher in women with 25 RBCs / hpf or greater

    • Smoking also increases risk.

  • Bottom line: women older than 60, with gross hematuria, and history of smoking have highest risk of urologic cancer.

    • Low risk, never smoking women, younger than 50 and fewer than 25 RBC/hpf - risk of urologic malignancy is less than 0.5%. 

  • In 2020, the AUA updated their guidelines to incorporate these gender-specific screening pathways, which are helpful to recognize and be  aware of:

    • Low risk women can undergo repeat urinalysis within 6 months, or cystoscopy/renal ultrasound

    • Intermediate risk women should undergo cystoscopy and renal ultrasound

    • High risk should undergo cystoscopy and CT urogram

  • Of course, keep your local urogyn / urologist aware of any patient for whom you have concern based on risk factors to discuss evaluation for urothelial cancers.

AUA/SUFU 2020 Microhematuria Algorithm

Interstitial Cystitis, feat. Dr. Edward Kim

Here’s the RoshReview Question of the Week!

A 41-year-old woman presents to your office for dysuria. She states that she has been having persistent urinary urgency and frequency for the past six months. She reports discomfort with bladder filling, pain with urination, and relief after voiding. A review of her history reveals normal fluid intake. A workup for pelvic pain performed by her primary care provider and gastroenterologist was negative. On physical exam, you note suprapubic tenderness. Her urinalysis and culture are negative. Which of the following is the best therapeutic option?

Check out if you answered correctly at the links above!


Today we welcome Dr. Edward Kim to the podcast. He is a urogynecology fellow at the University of Pennsylvania, performing research on a challenging topic: interstitial cystitis. Dr. Kim is looking to recruit more patients into a study on quality of life and patient education in IC — if you have questions or someone to refer, let us know by emailing us or contacting us with the form on the website!

Overview

  • IC: kind of a misnomer!

    • There is no conclusive evidence that there is an inflammation nor distinct pathology in the bladder interstitium.

    • Contemporary thinking: chronic pain condition related to or perceived to be originating from the bladder.

      • Newer terminology has been proposed: bladder pain syndrome.

      • In clinical practice, some patients seem to prefer ‘interstitial cystitis’ because to them is sounds more like a more medical diagnosis and they don’t want to be labeled as having a pain syndrome. So IC/BPS are used interchangeably.

Epidemiology

  • Can affect men and women but more common in women.

    • High prevalence in age 40s.

    • Don’t know the precise prevalence given complexity of syndrome.

Clinical Presentation

  • Variable

  • Persistent urinary urgency, urinary frequency, and pain or discomfort related to voiding.

    • Note that we say pain or discomfort. Some patients describe what they’re feeling as discomfort and not pain.

    • Classic: patient with these symptoms who had been treated multiple times for urinary tract infections despite having negative urine cultures. They also may report going to the bathroom frequently or spending a lot of their day on the toilet to relieve their urgency and discomfort or pain.

      • Many of these patients may also have associated conditions like irritable bowel syndrome, fibromyalgia, and pelvic floor muscle dysfunction.

      • They also may have concurrent psychiatric comorbidities such as depression or anxiety.

Diagnosis

  • American Urological Association: “An unpleasant sensation (pain, pressure, discomfort) perceived to be related to the urinary bladder, associated with lower urinary tract symptoms of more than six weeks duration, in the absence of infection or other identifiable causes.”

    • In other words, IC is a clinical diagnosis and diagnosis of exclusion.

    • Differential diagnosis should include:

      • Infection

      • Overactive bladder

      • Bladder or urethral cancer, gynecologic cancer

      • Uterine fibroids with compression effect on the bladder

      • Bladder stone

      • Bladder diverticulum

      • Foreign material such as synthetic mesh or suture

      • Neurologic conditions that may cause urinary retention in particular

      • Other chronic pelvic pain conditions such as endometriosis.

    • This is why it’s important to perform a thorough history and physical and obtain a post void residual and urine tests as an initial evaluation to rule out these other etiologies.

  • Hunner lesions can be seen on cystoscopy.

    • They are specific for IC, but they only are seen in about 10% of patients with IC.

  • Potassium sensitivity test KCl is instilled into the bladder.

    • This is not performed anymore due to its low sensitivity and specificity and also it’s very painful!

  • Urodynamics is not typically used to diagnose IC but it can be done to rule out other etiologies.

Treatment

  • Management strategy is multi-faceted.

  • First-line treatments are patient education, behavior and diet modification, and general stress management.

    • There is good evidence behind teaching patients bladder retraining where they learn to increase the interval between each voids.

    • Avoidance of things like artificial sweetener, caffeine, alcohol, spicy food, citrusy or acidic foods can help with symptoms.

      • Doesn’t require elimination, but helps to make informed decisions about diet.

    • Applying heat or ice packs to the suprapubic or perineal regions can also be helpful.

    • Pelvic floor muscle tenderness or dysfunction on exam —> consider pelvic floor PT.

  • Second-line treatments include oral medications and bladder instillation.

    • PRN medication is usually pyridium or over the counter AZO.

      • Warn patients that their urine will turn orange and may stain clothing.

    • Daily medications, the most commonly used ones are: amitriptyline, hydroxyzine and pentosan polysulfate sodium (Elmiron).

      • Note that Elmiron is the only FDA approved medication for IC. However, use of Elmiron has been associated with macular eye disease. Thus, in 2020, the FDA inserted a warning label to reflect this and use of Elmiron has been declining.

      • Between amitriptyline and hydroxyzine, currently there is more data on amitriptyline. Some patients find amitriptyline helpful in controlling their symptoms but some cannot tolerate its sedative and anticholinergic side effects.

    • If there is inadequate response to medications, then bladder instillation can be considered. This involves instilling a mixture of local anesthetic, heparin, DMSO, etc. via a catheter. Usually this involves repeated treatments.

  • Third-line treatment is hydrodistention.

    • Hyper-distention of the bladder under anesthesia for about 10 minutes and emptying the bladder.

      • The thought is that sensory nerves in the bladder are disrupted due to the hyper distention.

      • For patients who see prolonged and significant benefit, repeat treatments are considered.

    • If on cystoscopy Hunner lesions are found, they can be addressed with cautery, resection or injection with steroids.

  • Fourth-line treatments include neuromodulation using Botulinum toxin A injection into the bladder and sacral neuromodulation.

    • These techniques have been used for overactive bladder and neurogenic bladder but recent clinical trials have reported efficacy for interstitial cystits. 

  • Fifth-line treatment is cyclosporine A. Use is limited due to its side effects and paucity of convincing data.

  • Sixth-line and last resort is surgical diversion of the bladder with or without cystectomy.

    • Fortunately, patients seldom have to go past fourth-line treatments. As with any chronic pain condition, it is a difficult journey for many of them and it is critical for providers to listen and empathize with them.

Fecal Incontinence

Here’s your RoshReview Question of the Week!

Which of the following physical exam findings would be present in a woman with fecal incontinence and disruption of the external anal sphincter?

Find out the right answer by clicking on what you think the answer is, and find out how to save 20% on a RoshReview QBank Subscription for CREOG studying!


What is Fecal Incontinence? 

  • Definition

    • Part of accidental bowel leakage - where there is loss of normal control of the bowels. The other aspect of ABL is leakage of stool and gas (anal incontinence) 

    • Fecal incontinence - specifically is leakage of stool 

    • National Health and Nutritional Examination Survey defined it as: loss of solid or liquid stool or mucus at least once in previous 30 days 

  • How common is it?

    •  NHANES survey; 8.3% prevalence (in 4308 community dwelling adults 

    • Prevalence increases with age (2.6% in 20s to 15.3% in adults 70 and older) 

    • Likely underestimated since 75-80% of individuals with fecal incontinence don’t seek help or report them to their health care provider 

  • Risk factors 

    • Loose or watery stool 

    • Increased frequency of stools (more than 21 a week) ← ok, who is pooping more than 3x a day, and how can I get to this level of regularity  

    • Having 2 or more chronic illnesses 

    • Urinary incontinence, obesity, smoking, increasing age, decreased physical activity, anal intercourse, history of OASIS, history of pelvic radiation

What are the causes of fecal incontinence? 

  • Neurologic - ie. spinal cord injuries, spina bifida, and CVAs 

  • Non-neurologic

    • Most common in women are non-neurologic, usually after OASIS, may occur even remote from delivery 

    • Medications can also cause

Why do we care? 

  • Effect on quality of life

    • Significant effect 

    • Can cause depression, social isolation, shame, embarrassment, etc 

    • Can also worsen sexual function 

How do we evaluate? 

  • Screen!

    • ACOG says women with risk factors should be screened because they are often reluctant to disclose  

    • Should ask in women with other pelvic floor disorders 

    • Other risk factors that can be considered: Age >50, residence in nursing home, prior OASIS, history of pelvic irradiation, engagement in anal intercourse, presence of urinary incontinence, chronic diarrhea, diabetes, obesity, rectal urgency 

  • History and physical 

    • Ask about underlying neurological disorders and also modifiable risk factors for fecal incontinence (ie. obesity, diabetes, smoking, anal sex, certain medications that cause loose stools) 

    • Symptoms: what type of leakage (solid, liquid, gas, mucus), timing, frequency, severity (volume of loss), if there is fecal urgency, and how this affects their life 

    • There are a few validated surveys 

      • FI Severity Index, FI Quality of Life Scale, Fecal incontinence and Constipation Assessment Questionnaire 

    • Physical exam should include vaginal exam, exam of perineal area, and rectal exam (prior anal sphincter surgery/trauma) 

      • “Dovetail” sign - loss of normal puckering around the anus anteriorly

      • Digital rectal exam - sensitivity and specificity is overall low for detection of complete anal sphincter disruption 

      • Can also consider endoanal ultrasonography 

  • Other tests

    • Anal sphincter imaging/defecography/anorectal manometry not recommended for routine evaluation 

    • However, if anatomic defect or dysfunction is suspected or if clinical exam findings are inconclusive, can refer for ancillary testing 

    • Can also consider referring to urogynecology/colorectal surgery for further evaluation if not sure in clinic 

How do we manage and treat FI? 

  • Medical

    • Should be multidisciplinary approach 

      • Consider pelvic floor PT and management with urogynecology 

      • Also can consider gastroenterology

    • Medications

      • While loose stool itself does not cause fecal incontinence, it can worsen it and be a risk factor

        • Try something to bulk up stool - ie. fiber supplementation, dietary manipulation, bowel scheduling, etc 

      • Lifestyle management - should be offered in conjunction with everything else 

        • Wearing pads, diapers, briefs, etc 

        • Anal plugs ← 51% of people reported some sort of adverse event, like urgency, irritation, pain, soreness.

    • How effective are non-surgical treatments? 

      • Associated with modest short-term efficacy and low risk of adverse events, so should be recommended for initial management unless there is a fistula or rectal prolapse on exam 

      • However, lacking evidence for effectiveness of treatment beyond 6 months 

  • Surgical

    • Anal Sphincter Bulking Agents - not really surgery, kind of in between? 

      • Include things like dextranomer in stabilized hyaluronic acid, silicon biomaterial, carbon-coated beads 

      • May be effective in decreasing FI episodes up to 6 months 

    • Who is eligible for surgeries?

      • Not first line except for the two indications mentioned above (fistula or prolapse)

      • Proven to only provide short term improvement and have more complications than medical treatments/lifestyle modifications 

      • If patients fail medical treatments → can have surgery 

      • Refer to urogynecologist or qualified specialist to do them  

    • Neuromodulation 

      • Sacral nerve stimulation is possible for ABL 

        • Implantation of wire electrode near third sacral nerve root 

        • Two step → if initial testing is beneficial, then permanent battery is attached to wire electrode 

        • 2013 systemic review: 63% success rate (50% or greater reduction of FI) in the short term (<1 year), 58% in medium term (17-36 months), 54% (44-118 months)

      • Peripheral tibial nerve stimulation is not approved for FI 

    • Anal Sphincter Repair 

      • Sphincteroplasty can be considered with anal sphincter disruption and fecal incontinence symptoms who have failed conservative treatment 

      • Can do it end to end or overlapping sphincteroplasty 

      • Most studies:

        • Found to have similar outcomes 

        • Some evidence has shown that there can be significant deterioration in fecal incontinence over time after either type of repair, with 50% of women reporting symptoms 5-10 years after their repair

      • Most common adverse effect is wound infection (6-35% of cases!!) 

    • Other surgeries can be considered:

      • Radiofrequency anal sphincter remodeling 

      • Gracilis muscle transposition 

      • Diverting colostomy