Pessaries for the GYN Patient, feat. Dr. Edward Kim


What are pessaries?

  • Pelvic organ prolapse (or POP) and stress urinary incontinence (or SUI) are common problems that impact millions of women in the world.

  • A pessary is a support device placed vaginally that can be used to treat symptoms of POP, SUI, or both.

    • Pessaries are generally cost effective, well-tolerated, safe and can help avoid surgery.

      • For POP, up to 90% of patients report relief of symptoms like pressure and bulge.

      • For SUI, about half of patients report improvement in urinary symptoms.

History of the pessary

  • Historically, the first use of pessary for reduction of pelvic organ prolapse was described by Hippocrates.

    • He put a halved pomegranate soaked in wine into the vagina.

  • In 1860, Dr. Hugh Lenox Hodge, an ob/gyn faculty at the University of Pennsylvania, used newly developed vulcanized rubber to create a pessary shaped more anatomically.

    • Today, most pessaries are made of soft, flexible silicone thus considered non-allergenic.

The Modern Pessary

  • The most commonly used pessaries are ring, Gellhorn and donut. 

    • Ring pessary is a go-to in practice.

      • Subtypes: Ring without support

      • Ring with support (kinda looks like a mini frisbee),
        Ring without support with a knob

      • Ring with support with a knob.

        • The knob sits under the pubic bone and helps with stress urinary incontinence. So a ring with support and a knob will address POP and SUI. Rings can be removed by patients fairly easily.

    • A Gellhorn has a stem and a concave disc (kinda looks like a baby pacifier).

      • The concave disc part sits below the vaginal apex and creates somewhat of a suction.

      • The stem sits posteriorly and prevents the pessary from flipping around.

        • Gellhorns are little more difficult to place. Patients seldom can remove them on their own.

        • For removal, a provider usually needs to grasp the stem with their fingers or a ring forceps, gently wiggle it out to break the suction allowing for removal.

        • Gellhorns are generally used for more severe prolapse.

    • A donut (as the name implies) looks like a mini donut and it achieves its function by occupying the vagina.

      • A donut works better for more severe prolapse, as well, and difficult for patients to remove on their own.

Indication and counseling:

  • Patients with symptomatic POP or SUI who desire to avoid surgery, poor candidate for surgery, desire further childbearing, current pregnancy or within 12 months postpartum.

  • Contraindications include:

    • active pelvic infection,

    • latex allergy (as some inflatable pessary are composed of latex),

    • non adherence to care and follow up

  • Studies report a very wide range of patient acceptance of pessary: from 42 to 100%.

    • Patients who decline tend to be younger, sexually active,  nulliparous, or have severe POP or SUI and desire surgical correction.

    • But it also depends on the counseling. In our practice, we discuss pessary in the range of management options for POP and SUI. We sometimes use it as a bridge between now and surgery for patients who prefer symptom relief now.

Placement:

  • Placement comes with practice and it often involves trial and error.

  • There have been no identified reliable predictors of which size pessary should be tried first.

  • Start with a ring with support pessary (ring with support and a knob if also trying to address SUI).

  • Identifying the starting size (say, 3, 4, 5) comes with practice and pelvic exam. Wet it with warm water first.

    • You could use lubricant but if you use too much it may be too slippery for you to handle and also easier for it to be expelled.

  • Fold it in half like a taco, insert, and allow it to resume its disc shape in situ. Remember, it should NOT be painful. If the patient says it’s painful once it’s placed, then it is often too big.

    • Liken it to a corrective device like glasses or contact lens. When you first start using it, you notice that it’s there. But it should not be painful and with time you often forget it’s there.

  • Then have pt Valsalva.

    • It’s okay that you can see the pessary descend as long as it does not completely get expelled.

  • Then have them ambulate and go to the toilet and Valsalva with a toilet hat to catch the pessary if it does get expelled.

    • If it’s still in situ after that and patient has no discomfort, we send them home with it.

  • Placement of Gellhorn, donuts, and other types of pessaries are little different and may be best reserved for providers who have more experience with them. But I think ring pessaries can be something everyone can have in their toolbox.

Maintenance:

  • Patients who wish to and have the dexterity to maintain the pessaries on their own are instructed to take it out and clean with warm soapy water as often as they want but usually at least once a week.

    • If they are unable to, then typically they come to the clinic every 3-4 months for maintenance.

  • Patients with Gellhorn, donut, or other types of pessaries that patients cannot remove easily on their own also follow up every 3-4 months. At these visits, the pessary is removed, gently cleaned, and a speculum exam is done to assess for any excoriation or abrasion.

  • For postmenopausal patients without contraindication for topical vaginal estrogen, we typically have them use it to prevent significant vaginal excoriation or abrasion since atrophy can worsen these.

Complications:

  • Most common complaints are increase or change in vaginal discharge or odor. Reassurance and ruling out for vaginitis and bacterial vaginosis are reasonable next steps. Reports of vaginal bleeding long after placement warrants exam in the office.

  • Spontaneous expulsion or difficulty with voiding or defecation or pain often means a different size or shape should be tried.

  • Pessaries that have been left in situ and neglected for prolonged period of time should be taken seriously. Embedded pessaries may need removal under general anesthesia.

  • But overall, it is generally very safe.

Urinary Incontinence

On today’s episode, we visit with Dr. Kyle Wohlrab, who is an associate professor and urogynecologist at Brown University / Women and Infants Hospital of Rhode Island. He takes us through the basics of urinary incontinence.

Urinary incontinence is quite common: almost 1/3 of women in their lifetime. The Women’s Preventive Services Initiative even recommends annual standardized incontinence screening for women annually.

The mechanisms of incontinence include:
Stress - leakage with Valsalva (sneeze/laugh/cough/activity). Generally in small volumes.
Urge - aka overactive bladder; spasms or overactivity of bladder detrusor muscle that can prompt large volume leakage.
Mixed - a combination of the above; often one of the above types is “predominant.”

We review in the podcast many of the most important parts of a history and workup, but the most important aspect are the patient’s goals with respect to incontinence. This also will guide our therapy. Childbirth, obesity, and activities involving heavy weight bearing are some common risk factors.

One of the tests that can easily be performed, but many have limited experience with, is a simple cystometrogram. Essentially, one backfills the bladder. If during filling, one sees a rise in the meniscus, this is suggestive of detrusor overactivity. After filling with 200-300cc,, one can do a filled cough stress test to evaluate for stress incontinence.

Treatments vary by type of incontinence, but can be broken down into three categories for each type:
Stress - pelvic floor PT, vaginal inserts, and surgical therapy — midurethral sling, Burch urethropexy, urethral bulking.
Urge - pelvic floor PT and behavioral modification, medial therapies, and surgical therapies — neurostimulators.

For medical therapies for urge incontinence, antimuscarinic therapy is generally first line. Oxybutynin and trospium are the most commonly used medications in this class. Recall that antimuscarinic drugs have the “slow down” side effects of dry mouth/dry eyes, constipation, abdominal pain, and sedation. Newer medications in this class can have fewer side effects but can have difficulty with insurance coverage. Trospium is the newest medication that also doesn’t cross the blood-brain barrier, limiting neurologic side effects — especially useful in the elderly!

Beta agonists are another option for medical therapy with mirabegron. Rather than acting on muscarinic receptors, these act on beta agonists. These thus should be avoided in patients with uncontrolled hypertension.

When should someone refer to urogynecology? Dr. Wohlrab’s advice is to refer once someone has failed a line of therapy, or when patients begin looking for surgical therapy. Especially after listening today, we hope you’re comfortable with this workup and treatment!

Further reading from the OBG Project:
Urinary Incontinence – How to Make the Diagnosis in Your Office and When to Refer
Treating Urinary Incontinence Without Surgery: Options and Pearls
Prolapse and Stress Incontinence: Burch Procedure vs Midurethral Sling
Surgery for Urinary Incontinence – When the Sling’s the Thing