Fecal Incontinence
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Which of the following physical exam findings would be present in a woman with fecal incontinence and disruption of the external anal sphincter?
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What is Fecal Incontinence?
Definition
Part of accidental bowel leakage - where there is loss of normal control of the bowels. The other aspect of ABL is leakage of stool and gas (anal incontinence)
Fecal incontinence - specifically is leakage of stool
National Health and Nutritional Examination Survey defined it as: loss of solid or liquid stool or mucus at least once in previous 30 days
How common is it?
NHANES survey; 8.3% prevalence (in 4308 community dwelling adults
Prevalence increases with age (2.6% in 20s to 15.3% in adults 70 and older)
Likely underestimated since 75-80% of individuals with fecal incontinence don’t seek help or report them to their health care provider
Risk factors
Loose or watery stool
Increased frequency of stools (more than 21 a week) ← ok, who is pooping more than 3x a day, and how can I get to this level of regularity
Having 2 or more chronic illnesses
Urinary incontinence, obesity, smoking, increasing age, decreased physical activity, anal intercourse, history of OASIS, history of pelvic radiation
What are the causes of fecal incontinence?
Neurologic - ie. spinal cord injuries, spina bifida, and CVAs
Non-neurologic
Most common in women are non-neurologic, usually after OASIS, may occur even remote from delivery
Medications can also cause
Why do we care?
Effect on quality of life
Significant effect
Can cause depression, social isolation, shame, embarrassment, etc
Can also worsen sexual function
How do we evaluate?
Screen!
ACOG says women with risk factors should be screened because they are often reluctant to disclose
Should ask in women with other pelvic floor disorders
Other risk factors that can be considered: Age >50, residence in nursing home, prior OASIS, history of pelvic irradiation, engagement in anal intercourse, presence of urinary incontinence, chronic diarrhea, diabetes, obesity, rectal urgency
History and physical
Ask about underlying neurological disorders and also modifiable risk factors for fecal incontinence (ie. obesity, diabetes, smoking, anal sex, certain medications that cause loose stools)
Symptoms: what type of leakage (solid, liquid, gas, mucus), timing, frequency, severity (volume of loss), if there is fecal urgency, and how this affects their life
There are a few validated surveys
FI Severity Index, FI Quality of Life Scale, Fecal incontinence and Constipation Assessment Questionnaire
Physical exam should include vaginal exam, exam of perineal area, and rectal exam (prior anal sphincter surgery/trauma)
“Dovetail” sign - loss of normal puckering around the anus anteriorly
Digital rectal exam - sensitivity and specificity is overall low for detection of complete anal sphincter disruption
Can also consider endoanal ultrasonography
Other tests
Anal sphincter imaging/defecography/anorectal manometry not recommended for routine evaluation
However, if anatomic defect or dysfunction is suspected or if clinical exam findings are inconclusive, can refer for ancillary testing
Can also consider referring to urogynecology/colorectal surgery for further evaluation if not sure in clinic
How do we manage and treat FI?
Medical
Should be multidisciplinary approach
Consider pelvic floor PT and management with urogynecology
Also can consider gastroenterology
Medications
While loose stool itself does not cause fecal incontinence, it can worsen it and be a risk factor
Try something to bulk up stool - ie. fiber supplementation, dietary manipulation, bowel scheduling, etc
Lifestyle management - should be offered in conjunction with everything else
Wearing pads, diapers, briefs, etc
Anal plugs ← 51% of people reported some sort of adverse event, like urgency, irritation, pain, soreness.
How effective are non-surgical treatments?
Associated with modest short-term efficacy and low risk of adverse events, so should be recommended for initial management unless there is a fistula or rectal prolapse on exam
However, lacking evidence for effectiveness of treatment beyond 6 months
Surgical
Anal Sphincter Bulking Agents - not really surgery, kind of in between?
Include things like dextranomer in stabilized hyaluronic acid, silicon biomaterial, carbon-coated beads
May be effective in decreasing FI episodes up to 6 months
Who is eligible for surgeries?
Not first line except for the two indications mentioned above (fistula or prolapse)
Proven to only provide short term improvement and have more complications than medical treatments/lifestyle modifications
If patients fail medical treatments → can have surgery
Refer to urogynecologist or qualified specialist to do them
Neuromodulation
Sacral nerve stimulation is possible for ABL
Implantation of wire electrode near third sacral nerve root
Two step → if initial testing is beneficial, then permanent battery is attached to wire electrode
2013 systemic review: 63% success rate (50% or greater reduction of FI) in the short term (<1 year), 58% in medium term (17-36 months), 54% (44-118 months)
Peripheral tibial nerve stimulation is not approved for FI
Anal Sphincter Repair
Sphincteroplasty can be considered with anal sphincter disruption and fecal incontinence symptoms who have failed conservative treatment
Can do it end to end or overlapping sphincteroplasty
Most studies:
Found to have similar outcomes
Some evidence has shown that there can be significant deterioration in fecal incontinence over time after either type of repair, with 50% of women reporting symptoms 5-10 years after their repair
Most common adverse effect is wound infection (6-35% of cases!!)
Other surgeries can be considered:
Radiofrequency anal sphincter remodeling
Gracilis muscle transposition
Diverting colostomy